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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 11 of 11 Items
Showing 1 - 11 of 11 Items
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Journal Article
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Research

High performance of systematic combined urine LAM test and sputum Xpert MTB/RIF® for tuberculosis screening in severely immunosuppressed ambulatory adults with HIV

Bonnet MMB, Gabillard D, Domoua SK, Muzoora C, Messou E,  et al.
2023-03-08 • Clinical Infectious Diseases
2023-03-08 • Clinical Infectious Diseases
BACKGROUND
In people with HIV (PWH), the WHO-recommended tuberculosis four-symptom screen (W4SS) targeting those who need molecular rapid test may be suboptimal. We assessed the perf...
Conference Material
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Poster

Evaluation of the Optimising Malnutrition treatment (OptiMA) strategy amongst severely wasted children aged 6-59 months: randomized trial, Democratic Republic of Congo

Cazes C, Phelan KPQ, Hubert V, Boubacar H, Tshibangu G,  et al.
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
Journal Article
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Research

Systematic or test-guided treatment for tuberculosis in HIV-infected adults

Blanc FX, Badje AD, Bonnet MMB, Gabillard D, Messou E,  et al.
2020-06-18 • New England Journal of Medicine
2020-06-18 • New England Journal of Medicine
BACKGROUND
In regions with high burdens of tuberculosis and human immunodeficiency virus (HIV), many HIV-infected adults begin antiretroviral therapy (ART) when they are already seve...
Journal Article
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Research

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Sissoko D, Laouenan C, Folkesson E, M’Lebing A, Beavogui A,  et al.
2016-03-01 • PLOS Medicine
2016-03-01 • PLOS Medicine
Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health ...
Journal Article
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Commentary

Capacity building in sub-Saharan Africa as part of the INTENSE-TBM project during the COVID-19 pandemic

Ariza-Vioque E, Ello F, Andriamamonjisoa H, Machault V, González-Martín J,  et al.
2022-06-29 • Infectious Diseases and Therapy
2022-06-29 • Infectious Diseases and Therapy
Tuberculous meningitis (TBM) is the most severe and disabling form of tuberculosis (TB), with at least 100,000 cases per year and a mortality rate of up to 50% in individuals co-infected...
Journal Article
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Research

Favipiravir Pharmacokinetics in Ebola-Infected Patients of the JIKI Trial Reveals Concentrations Lower Than Targeted

Nguyen TN, Guedj J, Anglaret X, Laouenan C, Madelain V,  et al.
2017-02-23 • PLOS Neglected Tropical Diseases
2017-02-23 • PLOS Neglected Tropical Diseases
In 2014-2015, we assessed favipiravir tolerance and efficacy in patients with Ebola virus (EBOV) disease (EVD) in Guinea (JIKI trial). Because the drug had never been used before for thi...
Conference Material
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Abstract

Optimising malnutrition treatment in children 6-59 months: primary outcome of a randomized trial, Democratic Republic of Congo

Cazes C, Phelan KPQ, Hubert V, Boubacar H, Bozama LI,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research
INTRODUCTION
The Optimising MAlnutrition treatment (OptiMA) strategy aims to simplify current malnutrition treatment protocols for children with mid-upper arm circumference (MUAC)<12...
Journal Article
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Research

Mortality, AIDS-morbidity, and loss to follow-up by current CD4 cell count among HIV-1-infected adults receiving antiretroviral therapy in Africa and Asia: data from the ANRS 12222 collaboration

Gabillard D, Lewden C, Ndoye I, Moh R, Segeral O,  et al.
2013-04-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-04-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
In resource-limited countries, estimating CD4-specific incidence rates of mortality and morbidity among patients receiving antiretroviral therapy (ART) may help assess the effectiveness ...
Conference Material
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Poster

Optimising acute malnutrition treatment is non-inferior to standard protocol in uncomplicated severely wasted children: main secondary outcome of a randomised controlled trial in Democratic Republic of Congo

Cazes C, Phelan KPQ, Hubert V, Boubacar H, Tshibangu G,  et al.
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
Journal Article
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Commentary

Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: a case study in Guinea, West Africa

Carazo Perez S, Folkesson E, Anglaret X, Beavogui A, Berbain E,  et al.
2017-06-22 • PLOS Neglected Tropical Diseases
2017-06-22 • PLOS Neglected Tropical Diseases
During the large Ebola outbreak that affected West Africa in 2014 and 2015, studies were launched to evaluate potential treatments for the disease. A clinical trial to evaluate the effec...
Conference Material
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Slide Presentation

Optimising malnutrition treatment in children aged 6-59 months: ​Primary outcome of a randomised controlled trial in Democratic Republic of Congo​

Cazes C, Phelan KPQ, Hubert V, Boubacar H, Bozama LI,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research