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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 8 of 8 Items
Showing 1 - 8 of 8 Items
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Journal Article
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Research

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial

Schilling WHK, Mukaka M, Callery JJ, Llewelyn MJ, Cruz CV,  et al.
2024-09-12 • PLOS Medicine
2024-09-12 • PLOS Medicine

BACKGROUND

Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...

Journal Article
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Letter

Amoxicillin for severe acute malnutrition in children

Isanaka S, Adehossi E, Grais RF
2016-07-14 • New England Journal of Medicine
2016-07-14 • New England Journal of Medicine
Journal Article
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Research

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial

Isanaka S, Garba S, Plikaytis BD, McNeal MM, Guindo O,  et al.
2021-08-10 • PLOS Medicine
2021-08-10 • PLOS Medicine
BACKGROUND
Nutritional status may play a role in infant immune development. To identify potential boosters of immunogenicity in low-income countries where oral vaccine efficacy is lo...
Journal Article
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Research

Efficacy of a low-cost, heat-stable oral rotavirus vaccine in Niger

Isanaka S, Guindo O, Langendorf C, Matar Seck A, Plikaytis BD,  et al.
2017-03-23 • New England Journal of Medicine
2017-03-23 • New England Journal of Medicine
BACKGROUND
Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate eff...
Journal Article
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Research

Rotavirus vaccine efficacy up to 2 years of age and against diverse circulating rotavirus strains in Niger: Extended follow-up of a randomized controlled trial

Isanaka S, Langendorf C, McNeal MM, Meyer N, Plikaytis BD,  et al.
2021-07-02 • PLOS Medicine
2021-07-02 • PLOS Medicine
BACKGROUND
Rotavirus vaccination is recommended in all countries to reduce the burden of diarrhea-related morbidity and mortality in children. In resource-limited settings, rotavirus...
Journal Article
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Research

Extended follow-up from a randomized clinical trial of routine amoxicillin in the treatment of uncomplicated severe acute malnutrition in Niger

Isanaka S, Grantz KH, Berthé F, Schaefer MM, Adehossi E,  et al.
2020-03-01 • Journal of the American Medical Association (JAMA)
2020-03-01 • Journal of the American Medical Association (JAMA)
This study is an extended follow-up of a randomized clinical trial of routine amoxicillin use for infants experiencing uncomplicated severe acute malnutrition in Niger.
Journal Article
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Research

Routine amoxicillin for uncomplicated severe acute malnutrition in children

Isanaka S, Langendorf C, Berthé F, Gnegne S, Li N,  et al.
2016-02-04 • New England Journal of Medicine
2016-02-04 • New England Journal of Medicine
BACKGROUND
High-quality evidence supporting a community-based treatment protocol for children with severe acute malnutrition, including routine antibiotic use at admission to a nutri...
Journal Article
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Research

Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial

Coldiron ME, Assao B, Page AL, Hitchings MD, Alcoba G,  et al.
2018-06-26 • PLOS Medicine
2018-06-26 • PLOS Medicine
Antibiotic prophylaxis for contacts of meningitis cases is not recommended during outbreaks in the African meningitis belt. We assessed the effectiveness of single-dose oral ciprofloxaci...