Journal Article > Case Report/SeriesFull Text
ACG Case Rep J. 1 December 2020; Volume 7 (Issue 12); e00495.; DOI:10.14309/crj.0000000000000495
Abulaimoun S, Abushalha K, Reddymasu S, Teruya B, Natarajan N
ACG Case Rep J. 1 December 2020; Volume 7 (Issue 12); e00495.; DOI:10.14309/crj.0000000000000495
Hemophagocytic lymphohistiocytosis is a syndrome characterized by excessive immune activation. Timely diagnosis can be challenging, and prompt treatment is the only hope for survival. We present an adult patient with a history of alcohol dependence, who presented with fatigue, bilateral lower extremity edema, and orange-colored urine. Clinical workup revealed abnormal liver function tests, elevated ferritin, cytopenia, and lymphadenopathy. Eventually, he was diagnosed with hemophagocytic lymphohistiocytosis. This case report encourages gastroenterologists to maintain a high index of suspicion when a patient presents with liver failure, hyperferritinemia, and cytopenia because they may be the first healthcare professionals to evaluate these patients.