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Showing 1 - 20 of 76 Items
Showing 1 - 20 of 76 Items
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Evidence Brief

The power of community action in a changing climate

Tsotetsi N, Roca-Barcelo A, Pelembe L, Ahmed R, Neira L,  et al.
2025-11-01
2025-11-01
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Commentary

Does the type of treatment supporter influence tuberculosis treatment outcomes in Zimbabwe?

Mlilo N, Sandy C, Harries AD, Kumar AMV, Masuka N,  et al.
2013-06-21 • Public Health Action
Journal Article
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Research
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Research

Body mass index trajectories and association with tuberculosis risk in a cohort of household contacts in Southern Africa

Larsson L, Calderwood CJ, Marambire ET, Held K, Banze D,  et al.
2025-04-28 • Clinical Infectious Diseases
2025-04-28 • Clinical Infectious Diseases

BACKGROUND

Studies have demonstrated an inverse log-linear relationship between body mass index (BMI) and tuberculosis incidence. However, a person’s BMI is dyn...

A comparison of acceptability of contraceptive vaginal rings, pills, and injectables among cisgender women in Kenya and Zimbabwe: protocol for a mixed-methods study

Polis CB, Obare FO, Bruce IV, Banda C, Haddad LB,  et al.
2024-12-20 • VeriXiv
2024-12-20 • VeriXiv

BACKGROUND

Expanding contraceptive options could better meet users’ diverse needs and preferences. Annovera® is a contraceptive vaginal ring that pro...

Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

Ruef M, Emonet S, Merglen A, Dewez JE, Obama BM,  et al.
2024-03-11 • eClinicalMedicine
2024-03-11 • eClinicalMedicine
BACKGROUND
The increasing resistance of Enterobacterales to third-generation cephalosporins and carbapenems in sub-Saharan Africa (SSA) is a major public health concern. We did a sys...

Antimicrobial resistance in Enterobacterales infections among children in sub-Saharan Africa: a systematic review and meta-analysis

Kowalski M, Minka Obama B, Catho G, Dewez JE, Merglen A,  et al.
2024-03-08 • eClinicalMedicine
2024-03-08 • eClinicalMedicine
BACKGROUND
The burden of antimicrobial resistance (AMR) has been estimated to be the highest in sub-Saharan Africa (SSA). The current study estimated the proportion of drug-resistant...

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys

Huerga H, Farhat JB, Maman D, Conan N, Van Cutsem G,  et al.
2023-12-22 • PLOS Global Public Health
2023-12-22 • PLOS Global Public Health
Age and gender disparities within the HIV cascade of care are critical to focus interventions efficiently. We assessed gender-age groups at the highest probability of unfavorable outcome...

Descriptive epidemiology of the cholera outbreak in Zimbabwe 2018–2019: role of multi-sectorial approach in cholera epidemic control

Mashe T, Chaibva BV, Nair P, Sani KA, Jallow M,  et al.
2023-01-30 • BMJ Open
2023-01-30 • BMJ Open
OBJECTIVES
This study was conducted to explore the epidemiology and microbiological pattern of the cholera outbreaks that occurred in Zimbabwe from 2018 to 2019.

STUDY SETTI...

Descriptive Epidemiology of Typhoid Fever during an Epidemic in Harare, Zimbabwe, 2012

Polonsky JA, Martinez-Pino I, Nackers F, Chonzi P, Manangazira P,  et al.
2014-12-08 • PLOS One
2014-12-08 • PLOS One
Typhoid fever remains a significant public health problem in developing countries. In October 2011, a typhoid fever epidemic was declared in Harare, Zimbabwe - the fourth enteric infecti...

Scaling up HIV viral load monitoring in Manicaland, Zimbabwe: challenges and opportunities from the field

Nyagadza B, Kudya N, Mbofana E, Masaka S, Garone DB,  et al.
2019-12-21 • Public Health Action
2019-12-21 • Public Health Action
Background: Demand for viral load (VL) monitoring is expected to increase; however, implementation of the multifaceted VL testing poses numerous challenges. We report experiences from Mé...

Outcomes for efavirenz versus nevirapine-containing regimens for treatment of HIV-1 infection: A systematic review and meta-analysis

Pillay P, Ford NP, Shubber Z, Ferrand RA
2013-07-22 • PLOS One
2013-07-22 • PLOS One
INTRODUCTION
There is conflicting evidence and practice regarding the use of the non-nucleoside reverse transcriptase inhibitors (NNRTI) efavirenz (EFV) and nevirapine (NVP) in first...

Effectiveness of typhoid conjugate vaccine in Zimbabwe used in response to an outbreak among children and young adults: A matched case control study

Lightowler M, Manangazira P, Nackers F, Van Herp M, Phiri I,  et al.
2022-06-09 • Vaccine
2022-06-09 • Vaccine
BACKGROUND
Zimbabwe suffers from regular outbreaks of typhoid fever (TF), worse since 2017. Most cases were in Harare and a vaccination campaign with Typhoid Conjugate Vaccine (TCV) ...

Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis

Zheng Q, Luquero FJ, Ciglenecki I, Wamala JF, Abubakar A,  et al.
2022-09-01 • International Journal of Infectious Diseases
2022-09-01 • International Journal of Infectious Diseases
BACKGROUND
Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit...

Descriptive spatial analysis of the cholera epidemic 2008-2009 in Harare, Zimbabwe: a secondary data analysis

Luque Fernandez MA, Mason PR, Gray H, Bauernfeind A, Maes P
2010-11-13 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2010-11-13 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This ecological study describes the cholera epidemic in Harare during 2008-2009 and identifies patterns that may explain transmission. Rates ratios of cholera cases by suburb were calcul...

Elevation and cholera: an epidemiological spatial analysis of the cholera epidemic in Harare, Zimbabwe, 2008-2009

Fernandez MAL, Schomaker M, Mason PR, Fesselet JF, Baudot Y,  et al.
2012-06-18
2012-06-18
BACKGROUND
In highly populated African urban areas where access to clean water is a challenge, water source contamination is one of the most cited risk factors in a cholera epidemic....
2013-06-21 • Public Health Action

Treatment failure and mortality factors in patients receiving second-line HIV therapy in resource-limited countries

Pujades-Rodríguez M, Balkan S, Arnould L, Brinkhof MW, Calmy A
2010-07-21 • Journal of the American Medical Association (JAMA)
2010-07-21 • Journal of the American Medical Association (JAMA)
CONTEXT
Long-term antiretroviral therapy (ART) use in resource-limited countries leads to increasing numbers of patients with HIV taking second-line therapy. Limited access to furthe...

Variability of growth in children starting antiretroviral treatment in Southern Africa

Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H,  et al.
2012-09-17 • Pediatrics
2012-09-17 • Pediatrics
BACKGROUND
Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Ma...

Seasonal variations in tuberculosis diagnosis among HIV-positive individuals in Southern Africa: analysis of cohort studies at antiretroviral treatment programmes

Ballif M, Zurcher K, Reid SE, Boulle AM, Fox MP,  et al.
2018-01-11 • BMJ Open
2018-01-11 • BMJ Open
Seasonal variations in tuberculosis diagnoses have been attributed to seasonal climatic changes and indoor crowding during colder winter months. We investigated trends in pulmonary tuber...

Diagnostic performance and usability of the VISITECT CD4 semi-quantitative test for advanced HIV disease screening

Ndlovu Z, Massaquoi L, Bangwen NE, Batumba JN, Bora RU,  et al.
2020-04-03 • PLOS One
2020-04-03 • PLOS One
BACKGROUND
In sub-Saharan Africa, a third of people starting antiretroviral therapy and majority of patients returning to HIV-care after disengagement, present with advanced HIV dise...

Simplifying switch to second-line antiretroviral therapy in sub Saharan Africa: predicted effect of using a single viral load to define efavirenz-based first-line failure

Shroufi A, van Cutsem G, Cambiano V, Bansi-Matharu L, Duncan K,  et al.
2019-08-01 • AIDS
2019-08-01 • AIDS
BACKGROUND
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...