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Journal Article > Commentary

Improving rotavirus vaccine coverage: Can newer-generation and locally produced vaccines help?

Deen JL, Lopez AMZ, Kanungo S, Wang XY, Ahn DD, Tapia M, Grais RF
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Journal Article > Commentary
Effectiveness of oral cholera vaccine in Haiti
01-Mar-2015
Abstract
There are two internationally available WHO-prequalified oral rotavirus vaccines (Rotarix and RotaTeq), two rotavirus vaccines licensed in India (Rotavac and Rotasiil), one in China (Lanzhou lamb rotavirus vaccine) and one in Vietnam (Rotavin-M1), and several candidates in development. Rotavirus vaccination has been rolled out in Latin American countries and is beginning to be deployed in sub-Saharan African countries but middle- and low-income Asian countries have lagged behind in rotavirus vaccine introduction. We provide a mini-review of the leading newer-generation rotavirus vaccines and compare them with Rotarix and RotaTeq. We discuss how the development and future availability of newer-generation rotavirus vaccines that address the programmatic needs of poorer countries may help scale-up rotavirus vaccination where it is needed.
Subject Area
vaccinationinfections, viral
DOI
10.1080/21645515.2017.1403705
Published Date
14-Nov-2017
PubMed ID
29135339
Languages
English
Journal
Human Vaccines and Immunotherapeutics
Volume / Issue / Pages
Volume 14, Issue 2
Issue Date
21-Dec-2017
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