Journal Article
|Research

Experimental Treatment of Ebola Virus Disease with Brincidofovir

Dunning J, Kennedy SB, Antierens A, Whitehead J, Ciqlenecki I, Carson G, Kanapathipillai R, Castle L, Howell-Jones R, Pardinaz-Solis R, Grove J, Scott J, Lang T, Olliaro PL, Horby PW, RAPIDE-BCV trial team
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Abstract
The nucleotide analogue brincidofovir was developed to prevent and treat infections caused by double-stranded DNA viruses. Based on in vitro data suggesting an antiviral effect against Ebola virus, brincidofovir was included in the World Health Organisation list of agents that should be prioritised for clinical evaluation in patients with Ebola virus disease (EVD) during the West African epidemic.

Countries

Liberia

Subject Area

Ebola

Languages

English
DOI
10.1371/journal.pone.0162199
Published Date
09 Sep 2016
PubMed ID
27611077
Journal
PLOS One
Volume | Issue | Pages
Volume 11, Issue 9
Issue Date
2016-09-09
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