doi:10.1136/bmj.326.7402.1296 2003;326;1296- BMJ Nathan Ford Public health and company wealth http://bmj.com/cgi/content/full/326/7402/1296 Updated information and services can be found at: These include: Rapid responses http://bmj.com/cgi/eletter-submit/326/7402/1296 You can respond to this article at: service Email alerting the top left of the article Receive free email alerts when new articles cite this article - sign up in the box at Topic collections (1669 articles) Global health (671 articles) Regulation Articles on similar topics can be found in the following collections Notes To order reprints follow the "Request Permissions" link in the navigation box http://resources.bmj.com/bmj/subscribers go to: BMJTo subscribe to on 14 May 2007 bmj.comDownloaded from DEVELOPING WORLD 1296 BMJ VOLUME 326 14 JUNE bmj.com T he doctor’s role goes from care giver to undertaker. You talk to them about the cheapest method of burial. Telling them about the drugs is always kind of a cruel joke,” said Dr Chris Ouma of Kenya, where 2.5 million people are infected with HIV, and most cannot afford AIDS drugs. His comment reflects the difficult relationship between patient and doctor in the developing world, where millions are dying because they cannot access the medicines they need. This issue made international headlines during the World Trade Organisation’s Seattle meeting in December 1999. The high price of AIDS drugs became a banner of the world’s iniquities: on one side of the globe, Western multinationals made billions of dollars; on the other side, millions of people died from treatable infectious diseases. The pharmaceutical industry has responded to growing criticism by reducing some drug prices for some countries. But few patients in developing countries are aware of these efforts. Progress in reducing drug prices has depended mostly on market competition and media attention. Three years ago AIDS treatment cost $15 000 a year whether you lived in London or Lusaka. Today, some pharmaceutical companies provide discounts for sub-Saharan Africa. This is clearly good, but companies are not doing all they can. At the beginning of 2003, while one company was claiming that “the pace is picking up” in providing antiretrovirals to poor countries, another was charging $2000 a year more for its AIDS drug in Guatemala than in Switzerland. The responsibility to ensure access to essential medicines lies with governments. In 1996, the Brazilian government began to provide AIDS treatment for all in need by making their own version of expensive brand drugs, reducing costs by around 80%. Over 115 000 people in Brazil now receive antiretroviral treatment. But few have been able to follow Brazil’s example. Because market prospects, not health needs, drive production lines, drugs are developed for Western diseases while diseases of the developing world are ignored. In many clinics, doctors are forced to use old drugs that are toxic and don’t work well. For some diseases, no medicine is available at all. Buruli ulcer, a disfiguring and debilitating infectious disease, is a good candidate for antibiotic treatment, but because no drugs have been developed the only option is surgery, including amputation. Better business behaviour A group of major UK investors recently published a report urging drug companies to improve poor people’s access to medicines. The report proposed a framework of good practice to audit companies’ behaviour on issues like anti-monopoly enforcement, fair pricing and unfair use of political influence. The response of the Association of the British Pharmaceutical Industry to the concerned shareholders was: “The problem is not the attitude or commitment of the pharmaceutical industry. It is one of poverty, lack of infrastructure, and lack of political will.” Everyone’s fault, in other words, but not the industry’s. And yet the drugs industry can do much to contribute by reducing prices systematically for poor countries and directing some of its enormous drug development capabilities to neglected health needs. An international convention should be developed to ensure that new medicines are developed according to global health needs, and equitable drug pricing should be ensured through a mandatory framework. Patients are not consumers: they cannot choose between AIDS and leukaemia, and few can move from Guatemala to Switzerland. While medicines are treated like luxury consumer products, millions in poor countries will continue to go without the lifesaving medicines they need, and doctors will continue to play the role of undertaker, advising on funeral costs because it is the only option available. Nathan Ford access to medicines adviser, Médecins Sans Frontières, London EC1N 8QX. nathan.ford@london.msf.org Public health and company wealth When public protest at the price of AIDS drugs reached a peak, pharmaceutical companies seemed to take note, but the developing world’s health problems will never really be tackled as long as remedies for Western afflictions remain more profitable, writes Nathan Ford Bono and Bob Geldof urged Tony Blair to unite world leaders in the battle against AIDS when they met for a “Breakfast for Africa” last month “ HUGO PHILPOT/REUTERS 2003 on 14 May 2007 bmj.comDownloaded from